ncRNA name | Notch 1 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal endothelial cells (HRECs) |
Methods | siRNA transfection, TUNEL assay, Western blot, qPCR |
Expression pattern | associated |
Functional description | The apoptosis of HRECs was significantly decreased in cells transfected with Notch 1 siRNA compared to the blank vector group, and the expression of inflammatory cytokines in cells was also significantly decreased. |
PubMed ID | 29932924 |
Year | 2018 |
Title | The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway. |
Drug-related ncRNA | NO |
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